Decreased microRNA-181a and -16 expression levels in the labial salivary glands of Sj�gren syndrome patients
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چکیده
منابع مشابه
Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients
The aim of this study was to investigate the initiation and progression of autoimmune damage in the lesions of labial salivary glands (LSGs) from primary Sjögren's syndrome (SS) patients by examining the selective localization of T helper (Th) subsets such as Th1, Th2, Th17 regulatory T cells (T(regs)) and follicular T helper cells (Tfh). The expression of cytokines and transcription factors as...
متن کاملCommon T cell receptor clonotype in lacrimal glands and labial salivary glands from patients with Sjögren's syndrome.
Sjogren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration into lacrimal and salivary glands leading to symptomatic dry eyes and mouth. Immunohistological studies have clarified that the majority of infiltrating lymphocytes around the lacrimal glands and labial salivary glands are CD4 positive alphabeta T cells. To analyze the pathogenesis of T cells infiltrating...
متن کاملObservations of Nerve Terminals in Human Labial Salivary Glands
The existence of a motor innervation to the secretory and myoepithelial elements of salivary glands has been supported amply by physiological and pharmacological studies extending over a century (reviewed in Babkin, 1950 ; Emmelin, 1967) . However, the exact morphological nature of this innervation at the acinar level is less well established, and has been the subject of several conflicting rep...
متن کاملStructure and ultrastructure of the labial salivary glands in patients with cystic fibrosis.
The morphology of the labial salivary glands in subjects with and without cystic fibrosis has been studied by light and electron microscopy. The terms ;light' cell, ;dark' cell, ;clear' cell, and ;myoepithelial' cell are used to describe the four cell types distinguished at the level of the electron microscope. The dark cells were found to stain specifically with alcian blue at and above pH 1.0...
متن کاملDetection of AA-type amyloid protein in labial salivary glands.
OBJECTIVES Among the diverse forms of amyloidosis, secondary type is the most frequent one. Diagnosis of amyloid deposition is based on the identification of the fibrillary protein amyloid by means of Congo Red (CR) or crystal violet (CV) stains, but these techniques do not differentiate between the different types of amyloid fibrils. The aim of this study was to identify by immunofluorescence ...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2017
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2017.5407